SHIFT 45+ Max
A premium women's wellness gummy
built on Tongnan lemon pectin, for the body that's changing.
Dear Miss Yang,
We are developing a premium women's wellness supplement — SHIFT 45+ Max — for the United States and European Union markets. The product targets women aged 45 and above who are navigating the peri-menopausal and menopausal transition.
After studying your Mengxiaotai (檬小泰) product portfolio in detail, we have chosen Mengtai as our preferred manufacturing partner. Your vertical integration with Tongnan lemon — one of the world's three premier lemon-growing regions — gives this product a foundation no other supplier in Asia can match.
Below is the complete product specification along with ten critical questions. Your written answers will determine our path forward to sample stage.
Section IProject Overview
| Item | Specification |
|---|---|
| Product name | SHIFT 45+ Max |
| Brand owner | Sunside Sdn Bhd (Malaysia) |
| Target market | USA + European Union (women aged 45+, peri-menopause / menopause) |
| Format | Vegan pectin gummy candy |
| Daily serving | 3 gummies per day (2 morning + 1 evening) |
| Bottle size | 90 gummies × 2g = 180g per bottle (custom) — or please confirm if standard 120g is more economical |
| Supply period | 30-day supply per bottle |
| Flavor count | 2 flavors at launch: Lemon-Ginger Vegan · Lemon-Blueberry |
| Allergen requirements | Vegan Soy-free Gluten-free Dairy-free Honey-free Non-GMO |
| Shelf life target | 18 months minimum at 25°C / 60% RH |
| Annual volume target | Year 1 ≈ 25,000 bottles · Year 2 ≈ 60,000+ bottles |
Section IIFull Formula per 3-gummy serving
The product requires all nineteen functional ingredients at the exact doses specified below. Please confirm sourcing capability and per-unit cost for each.
A. Hero Ingredients (clinical-trial dose-matched)
| # | Ingredient | Dose | Required Source / Patent |
|---|---|---|---|
| i | Berberine Phytosome | 1,100 mg | Indena Berbevis® (Italy) — named patent required |
| ii | S-equol from Kudzu Root | 10 mg | Pueraria lobata fermented via Lactococcus 20-92 — non-soy source required |
| iii | Inositol myo + d-chiro 40:1 | 2,000 mg | Pharmaceutical grade |
| iv | Saffron Extract | 28 mg | Pharmactive Affron® (Spain) — named patent required |
| v | Ashwagandha Root Extract | 100 mg | Ixoreal KSM-66® (India) — named patent required |
| vi | Alpha-Lipoic Acid (R-ALA preferred) | 200 mg | Stability flagged — see Question 7 |
B. Metabolic & Structural Support
| # | Ingredient | Dose | Source / Patent |
|---|---|---|---|
| vii | Apple Cider Vinegar powder | 500 mg | Bragg-equivalent acetic acid, 5% AA |
| viii | Cinnamon extract (Ceylon, low-coumarin) | 200 mg | Sabinsa Cinnulin PF® |
| ix | EGCG (decaffeinated green tea) | 200 mg | Taiyo Sunphenon® 90DCF |
| x | Chromium picolinate | 200 mcg | Nutrition 21 Chromax® |
| xi | Vitamin D3 (cholecalciferol) | 2,000 IU | DSM Quali-D® |
| xii | Vitamin K2 MK-7 | 90 mcg | NattoPharma MenaQ7® |
| xiii | Magnesium glycinate (elemental) | 100 mg | Albion TRAACS® |
| xiv | Vitamin B6 (P-5-P active form) | 5 mg | Pyridoxal-5-phosphate |
| xv | Folate 5-MTHF | 400 mcg DFE | Gnosis Quatrefolic® |
C. Mengtai Exclusive (your existing capability)
| # | Ingredient | Dose | Notes |
|---|---|---|---|
| xvi | 12-strain patented probiotic | 5 billion CFU | Your pectin-coated FoodTalksTop30 panel (98% intestinal survival). Please recommend best 1-3 strains for women aged 45+. |
| xvii | Lemon-pectin prebiotic | 200 mg | Your patented lemon-pectin prebiotic |
| xviii | Natural edible lemon oil | 30 mg (~1-2 drops) | Your exclusive China-license lemon oil — positioned as the "Tongnan terroir signature" |
| xix | Vitamin C (from NFC Tongnan lemon) | 100 mg | From your existing Tongnan lemon source |
Approximately 4.8 g distributed across 3 × 2g gummies — roughly 1.6 g actives per gummy, which is a high-load formulation. Please address feasibility in Question 5.
D. Base Matrix (your standard, modified)
- Gelling base: lemon pectin (primary) + carrageenan (secondary)
- Sweeteners: stevia (Reb-M, fermented) + monk fruit + small allulose — please reduce maltitol and trehalose from your standard to achieve ≤ 2 g sugar per serving
- Acidulants: citric acid + sodium citrate
- Fat-soluble carrier: sunflower lecithin + MCT oil (for D3, K2, EGCG, ALA delivery)
- Coating: carnauba wax matte finish
- Color: only natural sources — turmeric + paprika oleoresin (Lemon-Ginger) or natural anthocyanin (Lemon-Blueberry)
- Strictly excluded: honey, gelatin, soy protein, artificial colors, artificial flavors, sucrose, gluten, dairy
Section IIITwo Flavor Profiles
Section IVPackaging Requirements
- HDPE recyclable bottle, matte finish, custom 180g size (90 × 2g gummies) — OR confirm whether your standard 120g bottle could accommodate 90 × 1.33g high-load gummies as an alternative
- Two flavors prepared with separate label artwork and SKU codes
- Tamper-evident seal · desiccant pouch included
- Export-ready labeling: English ingredient list + nutrition facts panel for the US market; EU food-supplement-compliant claim wording for the European market
- Future custom option: glass amber bottle variant for premium tier (Year 2)
Section VTen Critical Questions
Please address each question in your written reply. The answers determine production feasibility, timeline, and pricing.
Imported patented ingredient sourcing
Can your factory import and use the following six named-patent ingredients in our custom OEM batch?
- Indena Berbevis® (Italy)
- Pharmactive Affron® (Spain)
- Ixoreal KSM-66® (India)
- NattoPharma MenaQ7® (Norway)
- Gnosis Quatrefolic® (Italy)
- Sabinsa Cinnulin PF® (India / USA)
If yes, please indicate price-per-kg or per-unit cost, plus any supplier-side minimum order quantity.
Kudzu S-equol fermentation
Can your factory ferment kudzu root (Pueraria lobata) extract using Lactococcus 20-92 strain — similar to Otsuka's SE5-OH process — to produce S-equol at 10 mg per serving?
If your facility does not have this fermentation capability, can you source SE5-OH ingredient through a licensed supplier? This is our most critical ingredient — non-soy S-equol is the central brand differentiator of this product.
Probiotic strain recommendation
Among your 12 patented FoodTalksTop30 strains, which 1-3 strains have the strongest evidence for women aged 45+ peri-menopausal gut–immune–metabolic crossover? Please share strain names and recommended CFU distribution. Our target is 5 billion CFU per serving total.
Inositol 40:1 sourcing at 2g dose
Can you source pharmaceutical-grade inositol with the exact 40:1 myo-inositol to d-chiro-inositol ratio at 2,000 mg per serving? This is the bulkiest single active in the formula.
High-load gummy capacity
Total active mass is approximately 4.8 g across 3 gummies (~1.6 g per 2g gummy = 80% active load). Can your high-load pectin gummy technology achieve this density, or do we need to consider one of these alternatives?
- (a) 90 gummies × 2.5g each — lower density per gummy
- (b) 4 gummies daily × 1.5g actives each — more pieces per day
- (c) Reduce or remove certain non-hero ingredients
Custom 180g bottle vs. standard 120g
Can your production line produce custom 180g bottles (90 × 2g gummies)? Or is your standard 120g bottle (60 × 2g) significantly more economical — in which case we would adjust to a 20-day supply per bottle.
Alpha-Lipoic Acid stability
Alpha-Lipoic Acid 200 mg may have a sulfur note and stability concern in pectin gummy matrix over an 18-month shelf life. Has your factory worked with ALA in gummy formats before? Any preferred form (R-ALA versus racemic) or microencapsulation requirement?
Certificate of Analysis documentation
Please confirm that your factory can provide third-party CoA for every active ingredient per batch, covering:
- Identity (HPLC for botanicals, ICP-MS for minerals)
- Purity and heavy metals (lead, arsenic, cadmium, mercury under EU/US limits)
- Microbiological (total plate count, yeast/mold, pathogens)
- Active assay (% berberine, % isoflavones, etc.)
- Pesticide residues for botanical actives
- Allergen testing (soy / gluten / dairy / nut below detection limit)
- CoA available in English
Stability testing for 18-month shelf life
We require 18-month shelf life at 25°C / 60% RH storage. Please confirm that your factory can run accelerated stability testing (40°C / 75% RH for 6 months) to validate this. Critical parameters: probiotic CFU survival, vitamin D3 retention, K2 retention, and ALA stability.
Pricing, Minimum Order Quantity, and Lead Times
Please quote in USD, FOB Chongqing:
- (a) Sensory prototype — 50-100 bottles per flavor (100-200 total): cost and lead time?
- (b) Pilot batch — 500-1,000 bottles per flavor (1,000-2,000 total): cost per bottle, MOQ, lead time?
- (c) Production batch — 5,000-10,000 bottles per flavor (10,000-20,000 total): cost per bottle, MOQ, lead time?
- Payment terms: 30% deposit + 70% on shipment, or your standard terms?
Section VIRegulatory Documentation
Please confirm the availability of:
- ISO 9001 + ISO 22000 + HACCP + GMP certifications
- China food production license (SC certification)
- Export licenses for USA + European Union
- Vegan certification (or willingness to certify)
- Non-GMO Project compatibility, kosher / halal eligibility (kosher preferred for US retail entry)
- 1-year US FDA New Dietary Ingredient (NDI) eligibility per active
- European Union food supplement notification documentation (per country, as required)
Section VIIProject Timeline
| Phase | Milestone | Target Duration |
|---|---|---|
| Week 1-2 | Receive written quote, answered questions, sensory sample of closest existing product | This week |
| Week 3-4 | Confirm formula details and submit purchase order for sensory prototypes | 2 weeks after quote |
| Week 5-8 | Sensory prototype production (50-100 bottles per flavor) | 4 weeks |
| Week 9-10 | Sensory evaluation on our side (US + EU panels) | 2 weeks |
| Week 11-14 | Pilot batch production (1,000-2,000 bottles) | 4 weeks |
| Week 15-16 | Pilot batch QA and shipment to US warehouse | 2 weeks |
| Week 17+ | First DTC sale in USA market launch | Launch month |
Total: approximately 17 weeks from this request to first DTC sale. Please confirm whether your factory can meet this timeline, or what realistic adjustment is needed.
Section VIIINext Steps
If your factory can fully or partially deliver this product, please send us:
- Your written answers to the ten questions above
- An initial price quote — rough estimate is acceptable, we can refine later
- A sample of your closest existing gummy products (specifically NFC Lemon Juice Vitamin C Pectin Gummy + Probiotic Prebiotic Pectin Gummy) so we can verify base manufacturing quality before pilot
We're looking forward to building this partnership. Thank you for the detailed Mengxiaotai product card — your Tongnan lemon vertical is exactly the foundation we want for this product.
With kind regards,
中文版本 · Chinese Version
杨女士您好，
我们正在为美国 + 欧盟市场开发一款女性高端健康营养软糖 — SHIFT 45+ Max。产品面向 45 岁以上、正经历围绝经期 / 绝经期过渡的女性。
在仔细研究贵公司"檬小泰"的完整产品体系后，我们已选择貴厂作为首选制造合作伙伴。贵厂与铜南柠檬 (世界三大顶级柠檬产区之一) 的垂直整合，是亚洲任何其他供应商无法匹及的产品基础。
下面是我们的完整产品方案，附带 10 个关键问题。您的书面答复将决定我们进入打样阶段的路径。
第一节项目总览
| 项目 | 规格 |
|---|---|
| 产品名 | SHIFT 45+ Max |
| 品牌方 | Sunside Sdn Bhd (马来西亚) |
| 目标市场 | 美国 + 欧盟 (45 岁以上女性，围绝经期 / 绝经期) |
| 剂型 | 素食果胶软糖 |
| 每日服用量 | 每天 3 粒 (早 2 粒 + 晚 1 粒) |
| 瓶装规格 | 90 粒 × 2g = 180g / 瓶 (定制) — 或请确认贵厂标准 120g 是否更经济 |
| 供应周期 | 每瓶 30 天用量 |
| 口味数量 | 首发 2 个口味: 柠檬姜素食 · 柠檬蓝莓 |
| 过敏原要求 | 纯素 无大豆 无麸质 无乳 无蜂蜜 非转基因 |
| 保质期目标 | 25°C / 60%RH 条件下至少 18 个月 |
| 年度采购量 | 第一年约 25,000 瓶 · 第二年约 60,000+ 瓶 |
第二节完整配方 每 3 粒服用量
产品需要以下 19 种功能性成分，按精确剂量配置。请确认每种成分的采购能力和单价。
A. 核心明星成分 (临床试验剂量匹配)
| # | 成分 | 剂量 | 必需来源 / 专利 |
|---|---|---|---|
| i | 小檗碱磷脂复合物 | 1,100 mg | 意大利 Indena Berbevis® — 必需指定专利 |
| ii | 来自葛根的 S-equol | 10 mg | 葛根 (Pueraria lobata) 经 Lactococcus 20-92 菌株发酵 — 必需非大豆来源 |
| iii | 肌醇 myo + d-chiro 40:1 比例 | 2,000 mg | 药用级 |
| iv | 藏红花提取物 | 28 mg | 西班牙 Pharmactive Affron® — 必需指定专利 |
| v | 南非醉茄根提取物 | 100 mg | 印度 Ixoreal KSM-66® — 必需指定专利 |
| vi | α-硫辛酸 (R-ALA 优先) | 200 mg | 稳定性问题 — 详见 Q7 |
B. 代谢与结构支持
| # | 成分 | 剂量 | 来源 |
|---|---|---|---|
| vii | 苹果醋粉 | 500 mg | Bragg 同等品质，5% 乙酸 |
| viii | 锡兰桂皮提取物 (低香豆素) | 200 mg | Sabinsa Cinnulin PF® |
| ix | EGCG (脱咖啡因绿茶) | 200 mg | Taiyo Sunphenon® 90DCF |
| x | 吡啶甲酸铬 | 200 mcg | Nutrition 21 Chromax® |
| xi | 维生素 D3 (胆钙化醇) | 2,000 IU | DSM Quali-D® |
| xii | 维生素 K2 MK-7 | 90 mcg | NattoPharma MenaQ7® |
| xiii | 甘氨酸镁 (元素镁) | 100 mg | Albion TRAACS® |
| xiv | 维生素 B6 (P-5-P 活性形式) | 5 mg | 活性磷酸吡哆醛 |
| xv | 5-甲基四氢叶酸 | 400 mcg DFE | Gnosis Quatrefolic® |
C. 檬泰独家成分 (贵厂现有能力)
| # | 成分 | 剂量 | 说明 |
|---|---|---|---|
| xvi | 12 株专利益生菌 | 50 亿 CFU | 贵厂果胶包衣 FoodTalksTop30 菌株 (98% 肠道存活)。请推荐针对 45+ 围绝经期女性最佳的 1-3 株菌组合。 |
| xvii | 柠檬果胶益生元 | 200 mg | 贵厂专利柠檬果胶益生元技术 |
| xviii | 天然食用柠檬精油 | 30 mg (约 1-2 滴) | 贵厂中国独家食用柠檬油生产许可 — 定位为"铜南风土标识"元素 |
| xix | 维生素 C (来自铜南 NFC 柠檬汁) | 100 mg | 来自贵厂现有铜南柠檬来源 |
约 4.8 g 分布在 3 粒 × 2g 软糖中 — 每粒约 1.6 g 有效成分，属于高负载配方。可行性请在 Q5 中确认。
D. 基质 (贵厂标准，含修改)
- 凝胶基底: 柠檬果胶 (主) + 卡拉胶 (副)
- 甜味剂: 甜菊糖苷 (Reb-M 发酵法) + 罗汉果苷 + 少量阿洛酮糖 — 请减少贵厂标准配方中麦芽糖醇 + 海藻糖用量，目标每份糖分 ≤ 2g
- 酸味剂: 柠檬酸 + 柠檬酸钠
- 脂溶性载体: 葵花卵磷脂 + MCT 油 (D3、K2、EGCG、ALA 输送载体)
- 涂层: 巴西棕榈蜡哑光面
- 色素: 仅天然来源 — 姜黄 + 红椒油树脂 (柠檬姜) 或天然花青素 (柠檬蓝莓)
- 严格不含: 蜂蜜、明胶、大豆蛋白、人工色素、人工香料、蔗糖、麸质、乳制品
第三节两种口味方案
第四节包装要求
- HDPE 可回收瓶，哑光面，定制 180g 规格 (90 × 2g 软糖) — 或请确认贵厂标准 120g 瓶能否容纳 90 × 1.33g 高密度软糖作为备选
- 两种口味分别准备独立标签设计和 SKU 代码
- 防拆封封口 · 含干燥剂
- 出口标签准备: 英文成分表 + 营养成分表 (美国市场) + 欧盟食品补充剂合规声明用语 (欧洲市场)
- 后续定制选项: 玻璃琥珀瓶用于高端版本 (第二年)
第五节10 个关键问题
请在回复中逐一答复以下问题。这些答复决定了生产可行性、时间表和价格。
进口专利成分采购
贵厂能否进口并在我们的定制 OEM 批次中使用以下 6 种指定专利成分?
- Indena Berbevis® (意大利)
- Pharmactive Affron® (西班牙)
- Ixoreal KSM-66® (印度)
- NattoPharma MenaQ7® (挪威)
- Gnosis Quatrefolic® (意大利)
- Sabinsa Cinnulin PF® (印度 / 美国)
如可以，请告知每公斤或每单位价格，以及供应商端的最低采购量。
葛根 S-equol 发酵
贵厂能否使用 Lactococcus 20-92 菌株 (类似大塚 Otsuka SE5-OH 工艺) 发酵葛根 (Pueraria lobata) 提取物，生产每份 10 mg 的 S-equol?
如贵厂没有此发酵能力，能否通过授权供应商采购 SE5-OH 成分? 这是最关键的成分 — 非大豆来源的 S-equol 是本产品的核心品牌差异化。
益生菌菌株推荐
在贵厂 12 种专利 FoodTalksTop30 菌株中，哪 1-3 株菌对 45+ 围绝经期女性"肠-免疫-代谢"交叉作用证据最充分? 请提供菌株名称和推荐 CFU 剂量分配。我们目标是每份共计 50 亿 CFU。
肌醇 40:1 比例 2g 剂量
贵厂能否采购药用级肌醇，精确按 40:1 myo / d-chiro 比例配置，每份 2,000 mg? 这是配方中体积最大的单一有效成分。
高负载软糖容量
有效成分总质量约 4.8 g 分布在 3 粒软糖中 (每 2g 软糖含 1.6 g = 80% 有效成分负载)。贵厂高负载果胶软糖技术能否达到此密度，还是需要考虑以下替代方案?
- (a) 90 粒 × 2.5g 每粒 — 每粒密度较低
- (b) 每天 4 粒 × 1.5g 有效成分 — 每日粒数增加
- (c) 削减或移除部分非核心成分
定制 180g 瓶与标准 120g 瓶
贵厂生产线能否生产定制 180g 瓶 (90 × 2g 软糖)? 或贵厂标准 120g 瓶 (60 × 2g) 显著更经济 — 我们将调整为每瓶 20 天供应量?
α-硫辛酸 (ALA) 稳定性
α-硫辛酸 200 mg 在果胶软糖基质中 18 个月保质期内可能存在硫味和稳定性问题。贵厂是否处理过 ALA 在软糖中的应用? 优先形式 (R-ALA 与外消旋) 或需要微胶囊化吗?
CoA 分析证书文件
请确认贵厂能为每批次的每种有效成分提供第三方分析证书 (CoA)，涵盖:
- 鉴定 (HPLC 用于植物，ICP-MS 用于矿物质)
- 纯度和重金属 (铅、砷、镉、汞 < EU/US 限量)
- 微生物学 (总菌落数、酵母 / 霉菌、致病菌)
- 有效物含量 (小檗碱百分比、异黄酮百分比等)
- 农药残留 (针对植物成分)
- 过敏原测试 (大豆 / 麸质 / 乳 / 坚果 < 检出限)
- 英文版 CoA
稳定性测试 (18 个月保质期)
我们要求在 25°C / 60%RH 储存条件下保质期 18 个月。请确认贵厂可以进行加速稳定性测试 (40°C / 75%RH × 6 个月) 来验证。关键参数: 益生菌 CFU 存活、维生素 D3 保留、K2 保留、ALA 稳定性。
价格、起订量和交货时间
请按美元 FOB 重庆报价:
- (a) 感官评价样品 — 每口味 50-100 瓶 (共 100-200 瓶): 费用和交货时间?
- (b) 试产批次 — 每口味 500-1,000 瓶 (共 1,000-2,000 瓶): 每瓶价格、MOQ、交货时间?
- (c) 量产批次 — 每口味 5,000-10,000 瓶 (共 10,000-20,000 瓶): 每瓶价格、MOQ、交货时间?
- 付款条款: 30% 定金 + 70% 出货前付清，或贵方标准条款?
第六节监管文件要求
请确认以下文件可用性:
- ISO 9001 + ISO 22000 + HACCP + GMP 认证
- 中国食品生产许可 (SC 证)
- 美国 + 欧盟出口许可证
- 素食认证 (或愿意申请认证)
- 非转基因项目兼容性，犹太洁食 / 清真资质 (美国零售优先犹太洁食)
- 1 年期美国 FDA 新膳食成分 (NDI) 资格文件 (每个有效成分)
- 欧盟食品补充剂通报文件 (如需按国家)
第七节项目时间表
| 阶段 | 里程碑 | 目标时长 |
|---|---|---|
| 第 1-2 周 | 收到贵厂书面报价、问题答复、贵厂最接近现有产品的感官样品 | 本周 |
| 第 3-4 周 | 确认配方细节并下感官样品订单 | 报价后 2 周 |
| 第 5-8 周 | 感官样品生产 (每口味 50-100 瓶) | 4 周 |
| 第 9-10 周 | 我方感官评估 (美国 + 欧洲小组) | 2 周 |
| 第 11-14 周 | 试产批生产 (1,000-2,000 瓶) | 4 周 |
| 第 15-16 周 | 试产批 QA + 发往美国仓库 | 2 周 |
| 第 17+ 周 | 首次 DTC 销售 (美国市场上市) | 上市月份 |
总计: 从本申请到首次 DTC 销售约 17 周。请确认贵厂能否达到此时间表，或实际需要的调整。
第八节下一步
如贵厂能完全或部分交付本产品，请发送以下内容:
- 上述 10 个问题的书面答复
- 初步报价 (粗略估算即可，后续可细化)
- 贵厂现有最接近的软糖产品样品 (具体: NFC 柠檬汁维生素 C 果胶软糖 + 益生菌益生元果胶软糖)，以便我们在承诺试产前验证贵厂基础生产质量
期待与贵厂建立长期合作伙伴关系。再次感谢贵公司提供的詳細"檬小泰"产品资料 — 贵厂的铜南柠檬垂直产业链正是我们想要的产品基础。
此致敬礼